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doi:10.1016/j.jacadv.2023.100643 Higdon J

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In patients with chronic kidney disease, reduced reabsorption of carnitine can affect the availability of carnitine in muscles, leading to skeletal muscle atrophy and decreased exercise endurance [262]

It was demonstrated that the TXNIP-NLRP3 inflammasome complex production was activated in a time and dose-dependent manner by TMAO [60]
