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Description
Subunit interactions of glucose-6-phosphate dehydrogenase from human erythrocytes
As one key property which distinguishes tumor to normal tissue is hypoxia, we wondered if hypoxia itself might play a role in inhibition of the glyoxalase pathway as hypoxia-driven GLO1 deactivation was suggested already by previous studies 54,55

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The ratio of reduced to oxidized glutathione serves as a key indicator of the cellular redox potential, with even small changes in the GSH:GSSG ratio influencing protein function by altering cysteine oxidation and disulfide bond formation (Romero-Aristizabal et al., 2014)

The Sleep Disorders Inventory: An instrument for studies of sleep disturbance in persons with Alzheimers disease