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In vivo kinetics of thymidylate synthetase inhibition of 5-fluorouracil-sensitive and -resistant murine colon adenocarcinomas

Functional MRI studies link increased KYNA to reduced prefrontal activity, supporting its role in NMDAR hypofunction [105]

Their interaction complicates the disease and poses great challenges to clinical treatment and drug development ( 4.2.2 Function of curcumin in PD Up to now, the research on curcumin in the treatment of PD has been mainly conducted at the molecular level and in mouse models

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Interestingly, a study found that a short-term modified fasting regimen in middle-aged individuals reduced sleep arousals and periodic leg movements
