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Upon entry, Ca does not remain within the mitochondria but is swiftly expelled to restore basal levels via a complex network of retrotransporter proteins

ChREBP-deficient mice have decreased lipogenesis as well as reduced expression of ACC, ACLY, and FASN, but unchanged levels of SREBP-1c, suggesting that ChREBP and SREBP proteins are both required for the regulation of lipid synthesis genes (137)

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