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Phytochemicals, or bioactive compounds produced from plants, have received attention for their neuroprotective qualities, which include the ability to modulate BDNF expression and function

It is interesting to observe that ergothioneine is found in high amounts in certain plants, mushrooms and spirulina, that have been used and investigated for their medicinal properties (14,22,23)

doi: 10.1073/pnas.1416940111 31

After washed with 1 TBST three times, the membranes were further incubated with corresponding horseradish peroxidase (HRP)-conjugated secondary antibodies diluted in 1 TBST at room temperature for 1.5 h

In general, the target genes of Nrf2 are involved in glutathione synthesis, the elimination of ROS, xenobiotic metabolism, and drug transport