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Unlike apoptosis, paraptosis does not hinge on caspase activity but frequently hinges on the activation of mitogen-activated protein kinases (MAPKs), such as MAPK8/JNK, MAPK14/p38, and mitogen-activated protein kinase kinase 2 (MAP2K2/MEK2) [148]

Indeed, NQO1-Tg mice showed improved lipid metabolism management as revealed by relatively lower levels of lipotoxic species such as mono- and diacylglycerols and ceramide, accompanied by salutary long chain, unsaturated, hydroxy-fatty acids

Sex differences in hyperalgesia and allodynia were examined in ligated and unligated males, and ovariectomized and intact females in the CCI model

E., Webb E

Montassier E, Gastinne T, Vangay P, Al-Ghalith GA, des Bruley Varannes S, Massart S, Moreau P, Potel G, de La Cochetire MF, Batard E, Knights D