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Clinical trial endpoints and assessments The primary objective was to estimate the objective response rate (ORR) of patients with locally advanced or metastatic RMC treated with a combination of nivolumab plus ipilimumab

[2] [3] [4] Homocysteine is elevated in both vitamin B 12 and folate deficiency

Targeting ferroptosis constitutes a promising strategy for B cell-related complex diseases

Combinational treatment of AUR and proteasome inhibitor (PI) synergistically led to catastrophic cell death, reversible by NAC or protein synthesis inhibitor CHX, yet refractory to blockade of apoptosis, necroptosis or ferroptosis