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Ankar A, et al

In a previous study, transcriptomic profiling of brain regions involved in the brains reward circuitry (prefrontal cortex, dorsal striatum, nucleus accumbens, basolateral amygdala, ventral hippocampus, and ventral tegmental area) revealed considerable changes in transcript expression during the cocaine self-administration, withdrawal, and relapse phases, with the greatest changes detected in the re-exposure phase 40

Common positive reports include feeling more energetic during the day, subjectively better exercise performance, and a perception of "losing more fat and less muscle" compared to plain tirzepatide

Recipe for a Calendula cream: Oil phase Calendula oil 16g (to learn how to infused oils please check this post) Cocoa butter 4g Emulsifying wax 5g Beeswax 2g Water phase Distilled water 64g Glycerin 4g Xanthan gum 0.5g Cool down phase Preservative 1g Calendula extract 2g Vitamin E 0.5g Essential oil (vanilla) 1g You can infuse calendula dried petals with: sweet almond oil, macadamia oil, hazelnut oil, safflower oil, rice bran oil, fractionated coconut oil, argan oil, grapeseed oil or apricot kernel oil