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n-3 fatty acid supplementation for the treatment of dry eye disease

Ishizawa J, Kojima K, Chachad D, Ruvolo P, Ruvolo V, Jacamo RO, Borthakur G, Mu H, Zeng Z, Matre PR, Allen JE, Sarbassov DD, Neelapu SS, McDonnellT, Miranda R, Wang M, Kwak LW, Kantarjian H, Konopleva M, Davis RE, Andreeff M

Evidence has shown that L-carnitine can promote mitochondrial biogenesis by upregulating peroxisome proliferator-activated receptor-gamma coactivator-1alpha (PGC-1), a master regulator of mitochondrial biogenesis [14] and that L-carnitine promotes mitochondrial protein acetylation, a chemical modification that improves mitochondrial function and protects against stressors

Does a vitamin deficiency contribute to insomnia

We anticipate that future work on this protein will provide information that could be useful for developing strategies to age-associated declines in health and age-related human diseases