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Elevated TMAO downregulates hippocampal antioxidant enzyme MsrA, contributing to neuroinflammation and cognitive decline post-surgery in aged rats (143)

The GM metabolizes bile acids, converting unabsorbed primary bile acids to secondary bile acids via colonic microbiota's bile salt hydrolases (3), which enhance local intestinal immunity by inhibiting pathogenic growth (17)

It is necessary for muscle movement, heart, brain function, and other body functions

For best results, take 30 minutes before exercise or between meals