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Several types of ion channels in the ECs have been described including K + channels, Ca 2+ -activated K + channels, Cl channels, Ca 2+ channels, and Na + channels [24, 25, 51]

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In the lymph node, type I interferon secreted by dendritic cells promotes differentiation of naive T cells into effector T cells with cytotoxic capabilities

MMA and HCys levels can also be useful for differentiation of B 12 from folate deficiency: normal MMA and increased homocysteine levels are consistent with folate deficiency, and conversely, increased MMA levels without elevated folate levels indicate B 12 deficiency