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This led to its topical use as a dermatological ingredient to lessen melasma severity [100, 101]

Especially smokers should thus avoid cyanocobalamin and use other forms of B12 instead this will keep their exposure to cyanide down, and will even help with detoxification

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Kinetic modeling indicated that the NADH consumption reaction (complex I) exerted higher control on the Krebs cycle flux in HepM versus RLM and to a lesser extent in RHM