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doi: 10.1007/s00425-011-1488-7

Future studies should include larger, diverse cohorts and age-relevant microbiota

The prognosis of idiopathic pulmonary fibrosis

The prominent structural changes in aging vessels include increased arterial stiffness, reduced compliance, diminished vascular repair and regeneration capacity, and impaired endothelial cell function, ultimately leading to the development of atherosclerosis and calcification ( Oxidative stress is currently recognized as the "ultimate common pathway" for many chronic age-related diseases (Pitocco et al., 2013), as it can disrupt cellular metabolism and homeostasis, leading to endothelial cell damage

In cells that are stressed, there is a release of NRF2 which then is escorted from the cytoplasm into the nucleus by an importin protein, karyopherins [108]