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However, for the majority of proteins these reactions could occur only under non-physiological GSH/GSSG ratio (i.e., 1:1)

This mechanism is proposed as the results of the reinterpretation of toxicological and biological experiments in the light of our physico-chemical measurements of the fundamental properties of the involved molecules, the conjugates of the thiol-binding metals with the soluble and protein thiolome, and of the corresponding disulphides

Besonders wirksam und praktisch sind Glutathion-Infusionen : Bei vergleichbarer Dosierung tritt die Wirkung einer Infusion sprbar schneller ein als bei oraler Gabe

JCI Insight 2 , e90133 (2017)
In the cocaine-dependent patients, glutamate levels were normalized by a single oral administration of NAC (2.4 g) [128]