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The reader is referred to a comprehensive review on the actions of acetaldehyde (Correa et al., The logical extension that inhibiting the molecular mechanisms that initiate ethanol intake would also inhibit chronic alcohol intake proved to be wrong
It utilizes an aldehyde bisulfite to covalently bind to C145 (refs 94,95 )
Collectively, these findings indicate that disruption of the glucagon receptor not only modifies the gene expression profile of cells but also alters the pancreatic islet microenvironment
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Woo, and J
