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doi: 10.1080/10715762.2018.1468564

J., Acsadi, G., Elsheik, B., Schroth, M

A deeper understanding of the molecular mechanisms underlying circadian regulation and effects of metabolic hormones may help developing new therapeutic strategies for treating metabolic disorders

It was previously discussed that under certain circumstances, such as in acidic pH in vitro, CRP adopts a different pentameric configuration that exposes a hidden ligand binding site for non-phosphocholine ligands, which also enables CRP to bind to immobilized, denatured, and aggregated proteins, regardless of the identity of the native biomolecule [42]

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