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In parallel, AGE can reverse neuronal loss in the CA1 and CA2 regions of the hippocampus, increase the activity of antioxidant enzymes, including SOD and glutathione peroxidase (GP), as well as decrease the malondialdehyde (MDA) level in the A-exposed rat brain homogenate

The exogenous antioxidants comprise micronutrients and other exogenously administered antioxidants

Brain Endothelial Cells Are Exquisite Sensors of Age-Related Circulatory Cues
Am J Physiol Heart Circ Physiol 2018;314:H659-68

doi: 10.3390/ijms22031500 140 BaiYSunQ
