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Nutrients 13 , 1654 (2021)

MAPK3 can induce the expression of some anti-inflammatory cytokines (e.g

(PubMed) Bonetti A, Solito F, Carmosino G, Bargossi AM, Fiorella PL

doi:10.3390/molecules20058742 Lushchak VI

Effects of IGF-1 in physiological conditions The classical view of IGF-1 as an essential growth factor is expanded by findings of its significant metabolic effects whereby IGF-1 stimulation of its receptor serves as a signal that notifies cells about the availability of adequate nutrients, thus coordinating protein, fat, and carbohydrate metabolism in various cell types
