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The remaining IMS-MS parameters were set as follows: source temperature 120 C, sampling cone voltage 10 V, cone gas flow rate 20 L/h (N 2 ), desolvation temperature 350 C, desolvation gas flow rate 600 L/h (N 2 ), nebulizer gas pressure 6 bar, IMS gas flow rate 90 mL/min (N 2 ), IMS wave velocity and height at 500 m/s and 40 V, respectively

Currently, the commonly used tVNS in clinical practice includes taVNS, transcutaneous cervical VNS (tcVNS), and closed-loop taVNS (CL-taVNS)

Available online: 5.Rosenberg K., Twaddle S

[71] evaluated the effect of ADMSCs on NP cells in a non-physiological mechanical stimulation environment, and found that ADMSCs prevented NP apoptosis by inhibiting caspase-9 and caspase-3, and promoted the TIMP expression by increasing the amount of ECM, thereby inhibiting the effect of MMPs