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Experimental investigations commonly focus on its interaction with glutathione peroxidases, glutathione S-transferases, and redox-sensitive signalling proteins

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doi: 10.7759/cureus.34062

So, this cascade disabled the cell capacity to convert toxic lipid hydroperoxides (L-OOH), such as malondialdehyde (MDA) and 4-hydroxy-trans-2-nonenal, into less-toxic lipid alcohols (L-OH) and culminated in cell death from lipid peroxidation