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This perspective is often supported by neuroimaging studies (e.g., BOLD-fMRI) that report a mismatch between increases in glucose utilization (CMRglc) and oxygen consumption (CMRO) during brain activation

Grip strength as a simple yet powerful predictor of all-cause mortality [16:45]

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While these findings remain inconsistent and not yet clinically actionable, they underscore that VDR polymorphisms represent biologically plausible modifiers of individual responses to vitamin D status and potentially to exercise-related outcomes

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