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papain and bromelain) Flaxseeds and flaxseed oil Fish oil Garlic Ginger Gingko Lumbrokinase Melatonin Nattokinase Niacin Resveratrol Saffron (including extracts such as Krocina ) Supplements that may reduce warfarin's blood-thinning effect by increasing its breakdown include: Supplements that may promote clot formation, reducing the blood-thinning effects of warfarin, include the following: Supplements that may affect, or be affected by, aspirin (another common blood thinner): Vitamins that may affect aspirin: Vitamin E: High-dose vitamin E (~800 mg daily) may increase the blood thinning effects of aspirin and increase the risk of bleeding

The mechanism involves melanin