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However, MCC Glu was reduced ( g = 0.17) in the schizophrenia group that did not include the TRS patients

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doi: 10.1016/S0024-3205(99)00514-7 247 HuhKShinUSChoiJWLeeS
When melanocytes are hyperactivated by specific triggers UV radiation, post-inflammatory signals from acne or injury, hormonal changes (especially estrogen and progesterone in melasma), or genetic predisposition they produce excess melanin that accumulates in patches, creating dark spots, uneven tone and visible discolouration