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Vitamin B12 injections may not be suitable for people who have a history of: allergic reaction or sensitivity to cobalt or vitamin B12 Leber disease kidney disease or impaired kidney function Also, vitamin B12 injections may not be necessary for people without a deficiency

Although these therapies are often discussed together, they work through very different biological pathways

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The first day is intense: you descend 1,500 meters (4,921 ft) on a steep trail down to the Apurmac River, where you camp