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et al., 2022) revealed that capsaicin exerted an anti-proliferative effect on A549 cells as well as NCI-H23 cells through SLC7A11/GPX4 signaling, ultimately resulting in ferroptosis

Pfizer purchased exclusive global commercialization rights for the then-experimental treatment in December 2014 for $295 million upfront and a promise of up to $275 million in milestones

Hyper-activation of NLRP3 is consistently observed in PD patient samples and experimental models, and its genetic or pharmacological inhibition mitigates dopaminergic neurodegeneration

Regulation of the GSH biosynthesis pathway also takes place at the post-translational level by a redox mechanism

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