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It has not been approved by any major regulatory body for human medical use, and its safety and efficacy in humans have not been established in large-scale clinical trials

Clinical trials measuring body composition found that fat mass reduction occurred without corresponding increases in lean tissue mass, confirming the absence of anabolic muscle-building effects

Melatonin has an antioxidant role, like glutathione

Daratumumab in sensitized kidney transplantation: Potentials and limitations of experimental and clinical use

So even within KLOW, the evidence is uneven: strongest for the anchor, progressively more speculative for the supporting peptides