l-carnitine weight loss benefits The bright and the dark sides of supplementation: a systematic review | Journal of the International Society of Sports Nutrition Benefits of L-Carnitine
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when humans ingest Neu5Gc, small amounts can incorporate into our tissues (193, 194)

When the energy demand is high, inhibition of the isoform ACC2 of acetyl-CoA carboxylase increases fatty acid oxidation, while inhibition of the isoform ACC1 decreases fatty acid synthesis

In this small animal investigation, we demonstrate that chronic tobacco smoke exposure leading up to acute MI in rats is associated with greater histological extent of myocardial necrosis and consequent worse LV function
But, like with all supplements, it is good to talk with a doctor before starting
Running four or more increases side effect frequency by 2-4x without proportional benefit