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Am J Clin Nutr 108:612

[DOI] [PMC free article] [PubMed] [Google Scholar] 3.Baker SJ, Ignatius M, Johnson S, Vaish SK

Frequency and Duration of Administration: A single large dose might have a different effect profile than smaller, more frequent doses over an extended period

This occurred regardless of whether three episcleral veins had been cauterized, and remained permanently non-functioning
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