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DOI: Published online: June 30, 2021 Department of Anesthesiology and Pain Medicine, Dong-A University College of Medicine, Busan, Korea Corresponding Author: Tae Young Lee, Department of Anesthesiology and Pain Medicine, Dong-A University College of Medicine, 26, Daeshingongwon-ro, Seo-gu, Busan 49201, Korea, Tel: +82-51-240-5390 Fax: +82-51-247-7819 E-mail: [email protected] Received: June 24, 2020 Revised: October 3, 2020 Accepted: October 28, 2020 Copyright 2021 by Korean Association of Medical Journal Editors Articles published in Kosin Medical Journal are open-access, distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited

Their composition includes two subtypes of transmembrane cadherins, desmogleins, and desmocollins

Common range Community discussions reference 1-2 mg per day SubQ or 1-3% topical formulations

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