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Rat kidney transplant experiments were conducted as follows

10.1073/pnas.2410628121 [DOI] [PMC free article] [PubMed] [Google Scholar] Zhao Y, Zhang Y, Zhang J, Yang G (2021) Salvianolic acid B protects against MPP+-induced neuronal injury vAia repressing oxidative stress and restoring mitochondrial function

Pharmacological agents, such as rapamycin [40], metformin [250], or resveratrol [133] have been shown to stimulate protective autophagy, while inhibitors, such as 3-methyladenine or chloroquine, could be employed to restrain maladaptive autophagy during reperfusion [58]

Each component plays a defined role within the overall formulation strategy, contributing to an integrated performance framework rather than isolated effects