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This is more likely to happen if you already have sensitive or reactive skin

Conversion is fine for most healthy younger adults, but can be less efficient in people with MTHFR genetic variants (an estimated 25 to 40% of the population carries at least one variant), people with liver function decline (more common with age), and smokers and former smokers
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Titration Slowly increasing the dose over weeks instead of starting at the target dose

This is the advanced chemistry that allows top-tier water-based finishes to not just compete with, but often outperform, traditional oil-based products in durability
