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Description
Individual results vary
Can the capsules be opened to access the dry powder
This approach is especially useful for targets with a relatively short cellular half-life as (proteasomal/proteolytic) degradation of the protein target will induce the release of the reversibly bound covalent inhibitor that can engage in the inhibition of another target protein
Mass Spectrometry (MS): This confirms the identity of the molecule by verifying its precise molecular weight
Beyond a certain point, receptor saturation means diminishing returns
