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TMAO disrupts liver bile acid synthesis by inhibiting cholesterol 7--hydroxylase (CYP7A1), as bile acids regulate lipid metabolism via activation of the farnesoid X receptor

10.1007/s10654-023-01091-4 51 SessoH

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Se realiz un anlisis de corte transversal de dos grandes estudios prospectivos realizados en China el Shanghai Womens Health Study y el Shanghai Mens Health Study que incluyeron a 56,195 personas (edades, 40-75 aos), para evaluar la asociacin entre la ingesta diettica de colina y el diagnstico autoinformado de enfermedad del hgado graso (53)

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