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Research-grade FOXO4-DRI (FOXO4-D-Retro-Inverso) is a synthetic D-retro-inverso octapeptide (Arg-R-Arg-R-Gln-R-Arg-R-Arg), designed for controlled laboratory investigations of FOXO4-p53 disruption, selective clearance of senescent cells, and apoptosis induction in preclinical models

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Reproductive health research reveals significant applications in studying age-related endocrine dysfunction, with laboratory studies showing that FOXO4-DRI improves the testicular microenvironment and alleviates age-related testosterone secretion insufficiency by targeting senescent Leydig cells in aged male mice