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if any signs of an allergic reaction occur, the supplementation should be stopped and medical attention sought

Some patients report a warm or flushing sensation immediately following injection, which is normal

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(2017) Human LH and hCG Stimulate Differently the Early Signalling Pathways but Result in Equal Testosterone Synthesis in Mouse Leydig Cells in Vitro Reprod Biol Endocrinol 15(1):2

It is aligned with the winter solstice