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Grahek M

The high iron levels in CSCs, associated with their iron dependency, position ferroptosis as a promising approach for CSC- targeted therapy (52, 63)

doi: 10.1016/j.cell.2017.07.010 52

Combined inhibition of mTOR and CDK4/6 Is required for optimal blockade of E2F function and long-term growth inhibition in estrogen receptor-positive breast cancer

No, as an experimental senolytic peptide, FOXO4-DRI has no clinical approval or guideline recommendations for human use
