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PAI-1 (SERPINE1): Genetic Variants, Blood Clot Risk, Fibrosis, and Natural PAI-1 InhibitorsPlasminogen Activator Inhibitor (PAI-1) is an important enzyme in the regulation of the breakdown of blood clots and fibrosis

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This is the same logic that produced CagriSema (cagrilintide + semaglutide)

In the recovered cohort and the cohort without brain fog, upregulated terms included those related to the coagulation system, such as blood coagulation (for example, F13A1 , PROS1 ), platelet activation (for example, F2R , PF4 , PF4V1 ), platelet degranulation (for example, SELP , VCL , CLU ) as well as megakaryocyte development, immunoglobulin production and complement activation (Extended Data Fig

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