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On the other hand, ERCs upregulate antifibrotic genes such as HGF and matrix metalloproteinase-9 (MMP-9), further inhibiting fibrosis progression

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The microbiota can participate deiodination, sulfation, and glucuronidation processes of thyroid hormones because the gut works as a storage area for these hormones

3.6 Animal models supporting clinical findings While clinical investigations reveal correlations between eosinophils and IBD severity, causality is difficult to establish in patients