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This relevant clinical study was conducted on 41 patients, divided into non-smokers, smokers with normal lung function, and patients with COPD to check whether patients with mild COPD showed endothelial dysfunction of the pulmonary artery

J Am Soc Nephrol 17:29642966 Ebert T, Neytchev O, Witasp A, Kublickiene K, Stenvinkel P, Shiels PG (2021) Inflammation and oxidative stress in chronic kidney disease and dialysis patients

10.1016/j.exger.2021.111509 340 PayenV

however, from 2018 to 2020, the NAI resistance rate of influenza A(H1N1) pdm09 was as high as 1.3% globally with over 75% exhibiting the H274Y mutation, which provides high resistance to oseltamivir and peramivir (IC 50 increases by over 100-fold), and in comparison, the resistance rate of influenza A (H3N2) was less than 0.1%
