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Nanocarrier-based delivery systems(e.g., G4-AB-DOX/CuS, Sor@Fe-MOF) represent the most promising frontier, addressing key limitations of both monotherapy and combination approaches (253)

Manganese-induced alpha-synuclein overexpression aggravates mitochondrial damage by repressing PINK1/Parki-mediated mitophagy
It has been found that, in otherwise healthy HIV infected humans, the intracellular GSH levels in the peripheral blood mononucleocytes (PBMs) was significantly increased after oral administration of stabilized GSH

it involves harnessing or modifying the immune system rather than specifically targeting diseased tissue