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This may reflect differences across the studies including the duration of illness, age (in particular, the lower mean age of both healthy controls and MDD patients in the studies of occipital cortex), and medication use

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NAC works differently as a modified amino acidspecifically an acetylated form of cysteine with the molecular formula C5H9NO3S and molecular weight of 163.19 g/mol

In particular, we showed that in the presence of Cu 2+ ions, Semax is able not only to sequester metal ions, inhibiting A:Cu 2+ complex formation, but also to interact, most probably, with A:Cu 2+ oligomers, retarding the formation of protofibrillar and fibrillar species

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