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Trials showed good tolerability and placebo-like side effect profile

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The capacity of GSH to counteract oxidative stress and regulate cellular homeostasis positions it as a promising therapeutic target for a wide range of oxidative stress-related diseases [29,83,84,87]

The intracellular glutamate concentration is nearly 10-fold higher than the Km value, but intracellular cysteine concentrations approximate the apparent Km value [10] , indicating that cysteine may be a limiting substrate for GCL