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For the current method, the LOD and LOQ concentration was found to be 0.0001 mg/ml and 0.00018 mg/ml for NAC and 0.00015 mg/ml and 0.00045 mg/ml for Di-NAC, respectively

Tanner JM 1962 The development of the reproductive system

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Catabolism of BCAAs initiates at the transamination and transfer of nitrogen to -KG by branched-chain amino transferases (BCATs) to produce glutamate and their respective branched-chain -ketoacids (BCKAs) (Figure 1)

To shed more light on the identity of the substrate of arGSTs, we performed labelling experiments with H 2 18 O, exploiting the same principle of 18 O incorporation as described earlier