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Although many enzymes in one-carbon metabolism are affected by the sex hormones testosterone and estradiol, the main reasons for sexual dimorphism in glutathione metabolism are the effects of estradiol and the GSH regulatory motif, which includes the inhibition of GS and GCL by GSH itself [Figure 2B]

The titre of the vector stocks was estimated to be 5.4 10 8 transducing units per ml for the Gsto2 -shRNA and 5.1 10 8 transducing units per ml for the scrambled shRNA

MAO-B20 engages in conventional hydrogen-bonding interactions only with Leu163 and carbonhydrogen interactions with Ile197 and Ile198 (Figure 5F)