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Many adults with CVS have sympathetic nervous system dysregulation.10,25,26 Studies have reported increases in sympathetic tone in patients with CVS, recorded through various tests of autonomic function, such as postural adjustment ratio, heart rate variability, tilt table test, and sudomotor tests.10,2729 The most frequent finding in these reports was an adrenergic anomaly, in addition to coexisting abnormalities of vagal cholinergic function

DNA methylation changes in genes involved in inflammation and depression in fibromyalgia: a pilot study

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