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Initial contact with an antigen triggers one or other type of reaction, through a poorly understood mechanism that appears to involve the type of antigen, its size (large antigens tend to induce Th1 reactions), its concentration (low concentrations tend to induce Th2 responses), and stimulatory cofactors released by the APC (the presence of gamma interferon and/or IL-2 induces a Th1 response, while IL-4 induces a Th2 response)

10-year acceleration of aging (Akarsu et al

Autophagy and ubiquitination in cardiovascular diseases

It helps to maintain skin brightness and clarity

Pseudomonas aeruginosa OspR is an oxidative stress sensing regulator that affects pigment production, antibiotic resistance and dissemination during infection