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Occasionally histopathological examination of a biopsy specimen from a pigmented lesion is needed to rule out a malignancy

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Science 102 , 376377 (1945)

A 2026 retrospective longitudinal study using French national health claims data (20072020) identified 43 patients with LAL-D (17 infantile-onset, 26 later-onset), confirming that hepatomegaly, splenomegaly, and growth failure were the most frequent presenting features in infants and children, and highlighting the substantial healthcare utilization associated with both disease phenotypes (53)

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