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2017 ACC/AHA/HFSA focused update of the 2013 ACCF/AHA guideline for the management of heart failure: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Failure Society of America

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2000, Abdelrazik et al

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Previously, TMA and TMNO were considered non-toxic substances, but recently they have been considered potentially carcinogenic agents because of possible transformation to N-nitrosodimethylamine (NDMA)

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Liu Q, Garner P, Wang Y, Huang B, Smith H

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