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Dooley et al ., 2011)
( 10.1016/s0015-0282(0204679-4) [DOI] [PubMed] [Google Scholar] Lenzi A, Sgro P, Salacone P, Paoli D, Gilio B, Lombardo F, Santulli M, Agarwal A, Gandini L.2004
The density indicates some flexibility at R471 in both the inward-facing and ipratropium-bound structures, but both are pointing down towards the extracellular side and wedged between S157 and S467, preventing the H-bond network we observe in the occluded conformation (Fig
Badrie, N
Medications used to treat narcolepsy primarily target EDS and/or cataplexy
