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O(6)-Methylguanine-DNA methyltransferase (MGMT): A drugable target in lung cancer
Estimates place overall intracellular zinc concentration between 200-300 M, depending on cell type (38)
These prevalent genetic disorders reveal the evolutionary pressure on hosts to modulate the metabolic state of the red cell to improve survival during malaria, suggesting that acute, specific targeting of red cell glycolysis, the sole energy-generating pathway in mature erythrocytes, is a promising antimalarial approach
The patients presented with reductions in MDA concentration and increases in glutathione peroxidase but no alteration in RBC catalase or superoxide dismutase (SOD) activity [83]
A.FujimotoN.MatsumotoS.et al (2021)
